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July 20, 2020

Stroke Thrombolysis With Tenecteplase to Reduce Emergency Department Spread of Coronavirus Disease 2019 and Shortages of Alteplase

Author Affiliations
  • 1Department of Neurology, Dell Medical School, University of Texas at Austin, Austin
  • 2Ascension Texas, Austin
  • 3Department of Neurology, Geffen School of Medicine at UCLA, Los Angeles, California
JAMA Neurol. 2020;77(10):1203-1204. doi:10.1001/jamaneurol.2020.2396

Measures to reduce emergency department staff exposure to the severe acute respiratory syndrome coronavirus 2 have focused on screening and use of personal protective equipment. Reducing the time and intensity of interactions with individuals with known or suspected cases of coronavirus disease 2019 (COVID-19) is also desirable, insofar as such reductions do not compromise the quality or outcomes of care. The situation of an acute stroke emergency is a particularly vulnerable situation for exposure and transmission, since a substantial proportion of patients are unable to provide a history to screen them out for COVID-19.

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    1 Comment for this article
    Tenecteplase For Stroke Thrombolysis
    Khichar Shubhakaran, M.D.(Med),D.M.(Neurology) | Sr. S. N. Medical College, Jodhpur, India
    Tenecteplase is cheaper so it is a better option for poor, lower and middle income countries. For that reason we are using it instead of rtPA with no apparent significant disadvantage.