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Comment & Response
April 26, 2021

Risk Factors With Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy

Author Affiliations
  • 1Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China
JAMA Neurol. 2021;78(6):763-764. doi:10.1001/jamaneurol.2021.0890

To the Editor The study by Rubin et al1 aimed to develop a prognostic score to assess which patients are likely to experience chimeric antigen receptor (CAR) T-cell–associated neurotoxicity. We commend the authors for performing this interesting study, because these helpful results would be useful to guide clinical practice. However, after careful analysis, we would like to point out some important issues raised by the article.

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