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Comment & Response
July 6, 2021

Questions on Predicting Early Neurological Deterioration in Patients With Minor Stroke and Large-Vessel Occlusion

Author Affiliations
  • 1Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
  • 2Department of Radiology, University Hospital Basel, University of Basel, Basel, Switzerland
  • 3Department of Radiology, University of Calgary, Calgary, Alberta, Canada
  • 4Seaman Family Magnetic Resonance Research Centre, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada
JAMA Neurol. 2021;78(8):1020. doi:10.1001/jamaneurol.2021.2022

To the Editor We read with great interest the article by Seners and colleagues1 in which they investigated predictors of early neurological deterioration of presumed ischemic origin (ENDi) in large-vessel occlusion stroke with minor clinical deficits and developed a 4-point risk prediction score of ENDi. This is a common and probably underrecognized problem in large-vessel occlusion stroke, and characterizing patients at risk of ENDi is highly relevant for patient management.

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