Between 1930 and 1960, 450 British soldiers who were being assessed for epilepsy and other neurological disease after returning from duty in India were found to be affected by neurocysticercosis (NCC), the infection of the human nervous system by the cystic larvae of the pork tapeworm Taenia solium.1 This unexpectedly frequent finding brought attention to a globally common but yet poorly known disease. Introduction of the computed tomography scan in the 1970s substantially improved the premortem diagnosis of NCC and slowly began to unveil the scope of the problem. T solium is now known to be endemic in wide areas of the world, including Latin America, sub-Saharan Africa, Eastern Europe, and parts of Asia, including the Indian subcontinent, Southeast Asia, and large regions of China.2 Endemicity of T solium is deeply rooted in poverty and involves domestic pig raising and poor sanitary conditions. As such, the burden of neurologic disease associated with continued transmission falls mainly on impoverished rural populations. However, NCC cases are diagnosed worldwide, even where transmission is not endemic.2
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Garcia HH, Gonzalez AE, Gilman RH. Neurocysticercosis as an Eradicable Cause of Epilepsy: A Plan and Actions Are Needed. JAMA Neurol. 2021;78(9):1045–1046. doi:10.1001/jamaneurol.2021.2349
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.