This issue of JAMA Neurology includes a methodologically rigorous systematic review and meta-analysis examining the efficacy of benzodiazepines and antihistamines in patients with acute vertigo.1 Hunter and colleagues1 chose an important, common clinical problem, systematically searched for relevant evidence, and then assessed the studies for both quality and risk of bias. Their primary outcome was symptom control of vertigo at 2 hours measured by a visual analog score. Secondary outcomes included symptom control at later time points. Symptom control is clearly an important patient-centric outcome; therefore, their study is relevant and timely.