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Images in Neurology
October 23, 2023

Histologic Anatomy of Neurocysticercosis

Author Affiliations
  • 1Department of Neurologic Surgery, University of Miami Miller School of Medicine, Miami, Florida
  • 2Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida
JAMA Neurol. 2023;80(12):1371-1372. doi:10.1001/jamaneurol.2023.3739

A 23-year-old male patient presented with a tonic-clonic seizure. He had recently moved to the US from Haiti with no significant medical or seizure history. On presentation he was afebrile, alert, and oriented, with no motor or sensory deficit. Initial imaging demonstrated a well-circumscribed rim-enhancing lesion in the left frontal lobe (Figure 1). Complete blood cell count with differential erythrocyte sedimentation rate and C-reactive protein levels, blood culture results, and urine analysis results were all within normal limits, and results of HIV testing and computed tomography of chest, abdomen, and pelvis were unremarkable. Ultimately the patient was taken to the operating room for successful gross total resection of the cyst without wall rupture (Figure 1). Pathology confirmed a diagnosis of neurocysticercosis with histology demonstrating clear parasitic anatomy (Figure 2). The patient was successfully treated with anthelmintic therapy and has not experienced seizures since the surgery.

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