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September 1959

Serum Lipid and Cholesterol Levels in Cerebrovascular Disease

Author Affiliations

From the Departments of Neurology, Wayne State University College of Medicine and the Receiving Hospital of the City of Detroit.

AMA Arch Neurol. 1959;1(3):303-311. doi:10.1001/archneur.1959.03840030061006

Vascular disease of the brain is an important cause of death and disability in the United States. Recently it has been estimated that there are 2,000,000 people in the United States who are suffering from this condition.1 As a result, there has been increasing interest in the treatment of circulatory insufficiency resulting from atherosclerosis of the major cerebral vessels, since this is the commest single cause of neurological deficit. At present, therapeutic measures are directed toward maintenance of optimum blood pressure and cardiac output, prevention of embolization, and improvement of the collateral circulation by means of anticoagulant drugs or by surgical reconstruction of atherosclerotic carotid and vertebral arteries.2-10 Prevention or arrest of atherogenesis must await a more complete understanding of its cause.

Numerous studies have been reported of serum lipid and cholesterol levels in patients suffering from atherosclerosis of the coronary arteries and aorta, but we have been

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