The role of variations in the circle of Willis in brain diseases is unknown. They can alter angiograms and the results of carotid surgery. But do they contribute to diseases of the brain and to psychiatric disability?
A major problem in evaluating this question is variation in quoted percentages of anomalies. These variations arise in part from differences of opinion as to what constitutes a real change in anatomy. An observer tends to record those changes which he thinks will alter the circulatory pattern.
The following study was undertaken to find relationships that might exist between anomalies of the circle of Willis and other clinical or pathological data.
Anomalies were recorded in 139 randomly selected general hospital autopsies done at Kern General Hospital, Bakersfield, Calif., and in 256 almost consecutive psychiatric hospital autopsies done at Fairfield State Hospital. All cases were examined by one person (myself) during a period
HOWIE DL. Incidence of Anomalies of the Circle of Willis in Psychiatric Patients. AMA Arch Neurol. 1959;1(4):425–426. doi:10.1001/archneur.1959.03840040069002
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.