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January 1961

Brain Metastases: Pathological— Electroencephalographic Study

Author Affiliations

Branch of Electroencephalography and Clinical Neurophysiology, National Institute of Neurological Diseases and Blindness, National Institutes of Health, U.S. Public Health Service, Department of Health, Education and Welfare.

Arch Neurol. 1961;4(1):8-20. doi:10.1001/archneur.1961.00450070010002

Introduction  The value of electroencephalography in the diagnosis and localization of primary tumors of the brain is well recognized and established since the pioneer work of Grey Walter.1,2 Less definite information is available regarding the efficacy of the method in confirming or revealing cerebral metastases: the reports are generally confined to relatively small series of metastatic tumors, accompanied by neurologic manifestations3-5 and in many cases verified exclusively or mostly through surgical intervention.4,6-8 Other reports either deal with isolated cases9-13 or treat the EEG aspect of relatively large series of brain neoplasms without separate analysis of gliomas and metastases.14-19Yet diagnostic problems of primary and secondary brain tumors are often quite different. The patient with a primary tumor may be in good general health, his clinical state being largely the result of the neurological lesion per se. Patients with matastatic tumors are usually in very

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