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March 1961

Cerebral Arterial Thrombosis in Children: Review of Literature and Addition of Two Cases in Apparently Healthy Children

Author Affiliations

From the Department of Neurological Surgery, Albert Einstein College of Medicine, and the Neurosurgical Service of the Bronx Municipal Hospital Center, New York.

Arch Neurol. 1961;4(3):258-267. doi:10.1001/archneur.1961.00450090024004

Occlusive disease of the carotid and basilar arteries has been studied extensively in adults, and with the advent of cerebral angiography, accurate anatomical diagnosis during life is now possible. Moreover, this method of investigation is being used with increasing frequency in pediatric problems, with the result that arterial occlusive disease is being encountered in a higher proportion of cases than might have been suspected. This report of two cases in children with major intracranial vascular occlusion was prompted by the infrequence of well-documented cases in the literature. The necropsy findings in the fatal case are presented, a review of selected cases from the literature is included in the discussion, and emphasis is placed upon the aid afforded by carotid angiography.

Report of Cases  Case 1.—An 11-year-old Negro girl with a left hemiparesis was admitted to the Bronx Municipal Hospital Center on Sept. 21, 1957. The child had been in good

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