What will drugs do towards ridding the patient of his paralysis? Nothing. No drugs can do anything whatever, good or bad, for cerebral softening. Softened brain is not brain at all; it is dirt in the brain. . . . He who is treating by drugs hemiplegia owing to softening or to a clot is treating a hole in the brain.—John Hughlings Jackson.12
HORWITZ NH. Therapeutic Problems in Cerebrovascular Disease: The Experimental Use of Plasmin in Dogs. Arch Neurol. 1961;4(4):391–398. doi:10.1001/archneur.1961.00450100039006
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