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April 1961

Trichinella Spiralis Infection of the Central Nervous System: Report of a Case and Review of the Literature

Author Affiliations

From the Study Program in Human Health and the Ecology of Man, and the Department of Medicine (Neurology), the New York Hospital-Cornell Medical Center.

Arch Neurol. 1961;4(4):407-417. doi:10.1001/archneur.1961.00450100055008

Introduction  Although the reported incidence of trichinosis varies with method of observation and observer,27,29,83 it was estimated in a U.S. Public Health report in 1953 that 350,000 persons are infected each year and that approximately 16,000 of these infections produce symptoms of clinical significance.21 In spite of these large numbers, reports of focal damage in the central nervous system as a manifestation of trichinosis are rare. As of 1953 there were only 31 well-documented instances of such infection.34 Since 1953, however, new methods of diagnosis and treatment have become available; it is appropriate, therefore, to review the literature once again with reference to this syndrome, together with the presentation of the present patient.

Report of Case  History.—This 45-year-old white woman was admitted to the New York Hospital on Aug. 4, 1960, having been unresponsive for 24 hours. She had been in her usual state of adequate

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