Concussion is a transient reversible alteration of the central nervous system of immediate onset resulting from an impact to the head. It is defined physiologically by a temporary abrogation of certain reflex functions, and pathologically by the absence of gross destruction of brain substance, but presence of finer cellular changes; both psysiological and pathological evidences indicate a particular affection of the brain stem.Denny-Brown and Russell5 distinguished an acceleration concussion of the freely movable head from a compression concussion of the rigidly fixed head. The present investigation is limited to the neuropathology and mechanics of experimental acceleration concussion in cats; the relationship of acceleration concussion to compression concussion will be discussed on the basis of these findings.Two experimental series are reported in this article: the first part describes the histopathology of cats with concussions compared to the symptoms and the mechanical forces involved. The second part describes
FRIEDE RL. Experimental Concussion Acceleration: Pathology and Mechanics. Arch Neurol. 1961;4(4):449–462. doi:10.1001/archneur.1961.00450100097012
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