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February 1962

The Chemistry of Brain Metabolism in Health and Disease: Monograph in American Lectures in Living Chemistry.

Arch Neurol. 1962;6(2):169-170. doi:10.1001/archneur.1962.00450200083010

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In this short volume the authors have attempted only to present some of the highlights of biochemistry as it pertains to the nervous system, accompanied by a bibliographic guide to original papers, symposia, and reviews.

The first thirty-four pages summarize basic knowledge concerning the metabolism of oxygen and carbohydrate in the brain, in vivo and in vitro, and the changes observed during maturation and aging and in disease states. Amine metabolism in the brain is rather systematically and comprehensively treated in seventeen pages, and a concise summary of amino acid metabolism is given in thirteen pages.

Some of the remaining portions of the book are less well organized. The two chapters entitled "Transport Phenomena" (ten pages) and "Lipid Metabolism" in the Brain (twenty-three pages) consist of sections which follow one another in no clearly discernible logical order, and some of them are related only tangentially to the chapter heading. The

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