Quain,1 in 1844, was the first to describe a carotid-basilar anastomosis. Padget2 has given the name "persistent trigeminal artery" to this anastomosis because of its close relationship to the gasserian ganglion and the fifth cranial nerve. In the early stages of development of the human embryo the trigeminal artery is the main source of arterial blood to the hindbrain. With the formation of the vertebral-basilar system to supply the hindbrain, the trigeminal artery usually undergoes regression and disappears by the time that the embryo reaches the 14 mm. stage.
Report of a Case
A 46-year-old Negro woman who had been in good health until the day of admission awoke with a severe headache and weakness of the left side of the body. Upon admission the patient was slightly drowsy, moderately confused, and incontinent. There was a left homonymous hemianopsia, a depressed left corneal reflex, a mild left-central facial
GANNON WE. Malformation of the Brain: Persistent Trigeminal Artery and Arteriovenous Malformation. Arch Neurol. 1962;6(6):496–498. doi:10.1001/archneur.1962.00450240074009
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