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November 1962

Sarcoidosis of the Central Nervous System: A Case with Postmortem Studies

Author Affiliations

Present address: National Institutes of Health, Neurological Diseases and Blindness (Dr. Camp).; From the Department of Medicine (Neurology), New York Hospital, Cornell Medical Center, New York.

Arch Neurol. 1962;7(5):432-441. doi:10.1001/archneur.1962.04210050068008

The granulomatous lesions characteristic of sarcoid have been known to involve practically every organ or organ system of the body, especially the lymph nodes, lungs, spleen, liver, and skin. In approximately 3% of cases the central nervous system is involved.1 The number of cases reported with postmortem examination, however, has been small. For this reason, and because the present study has revealed unusual features of central nervous system sarcoidosis, the following is presented.

Report of a Case  A 17-year-old Negro schoolboy was seen for the first time at the New York Hospital on Jan. 16, 1960, twenty-four hours after 3 epileptiform seizures within 2 hours.He had been in good health until February, 1956, four years before admission, when he noted gradual weight loss, night sweats, and a chronic cough which was occasionally productive of large amounts of sputum. Six months later he began having headaches, and cervical adenopathy

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