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July 1963

Ultrastructure and Metabolism of the Nervous System: Research Publications of the Association for Research in Nervous and Mental Disease.

Arch Neurol. 1963;9(1):103. doi:10.1001/archneur.1963.00460070113015

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This volume is the latest publication of the annual proceedings of the Association for Nervous and Mental Diseases which was held in New York in December, 1960. It deals with chemistry and morphology—two most important disciplines involved in the studies of the nervous system. There are fifty contributors and discussants comprising the 24 papers of these proceedings. Despite the title of the Proceedings, however, only three papers are primarily concerned with the morphological organization of the nervous system utilizing electron microscopy. The three contributions on ultrastructure give the reader a lucid account of the fields of research of three expert investigators. One important contribution of electron microscopy is, as Dr. Sarah Luse points out, the characterization of central nervous tissue by its greatly restricted extracellular space. Cells and their processes fill the entire brain leaving a uniform extracellular space of only 3% to 5% of the total volume in contrast

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