[Skip to Navigation]
February 1964

Limbic Nuclei of Thalamus and Connections of Limbic Cortex: V. Thalamocortical Projection of the Magnocellular Medical Dorsal Nucleus in Man

Author Affiliations

From departments of anatomy and neurology and the Warren Anatomical Museum, Harvard Medical School, and the Neurological Unit, Boston City Hospital.

Arch Neurol. 1964;10(2):165-180. doi:10.1001/archneur.1964.00460140051008

Introduction  Comparative studies of the thalami of various mammals,2 including marsupials,5 the rabbit,28,61,80 rodents,25,29,33 the sheep,62 carnivores,30,60,79 and primates,10,15,72-75 demonstrate a progressive phylogenetic enlargement and differentiation of nucleus medialis dorsalis (MD), in parallel with the development and elaboration of the frontal lobes (ie, opercularization of insula). In man, MD is the largest member of the internal segment of the dorsal thalamus; the anterior, lateral, and inferior borders of the nucleus are clearly delineated by the internal medullary lamina in myelin-stained sections and are visible even in unstained slices of the fresh brain. The precise cytoarchitectonic differentiation of MD from neighboring nuclei—the midline and intralaminar nuclei and the medial pulvinar—is difficult, however, at several points.54,65A number of authors (Clark,10 Walker,72-75 Sheps,65 Toncray and Krieg,69 Olszewski,54 Dekaban18) have recognized in primates two or three and sometimes four

Add or change institution