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Mechanisms of Demyelination is the published proceedings of a symposium held at the Brain Research Institute at UCLA in 1962. The major objective of the Conference was to bring together scientists working on various aspects of myelin structure as well as the demyelinating process. An outstanding group of investigators in ultrastructural, biochemical, and immunological aspects of this field participated in the meeting. Each of the major essayists was apparently given ample time to cover his own field in depth, and also participated in a panel discussion in which representative cases of demyelinating disease were used as a basis for evaluating existing concepts.
Immunological mechanisms received the greatest emphasis at this conference, and in this regard the chapters by Drs. Carl M. Pearson, Robert A. Good, and Byron H. Waksman are of particular interest. Their representations, which constitute a major portion of the book, are as comprehensive a review of the