[Skip to Content]
[Skip to Content Landing]
May 1964

Sphincter Involvement in Ocular Myopathy

Author Affiliations

From The Johns Hopkins University School of Medicine and Hospital, and the Baltimore City Hospitals.

Arch Neurol. 1964;10(5):446-448. doi:10.1001/archneur.1964.00460170016002

In patients with ocular myopathy, weakness may not be restricted to extraocular muscles. Involvement of muscles of mastication, of face, those innervated by lower cranial nerves and neck muscles commonly develops, and even weakness of the extremities may occur.1-3 Two patients with this diagnosis are presented in whom involvement of external anal sphincter muscles was demonstrated.

I. Clinical Findings  CASE 1.—At the age of 46 years, this man (hospital No. 1051091) first complained of double vision. Shortly thereafter, the right eye turned out and the lid on that side drooped, prompting three corrective operative procedures. A similar divergent squint developed in the left eye six years later. In addition to these ocular complaints, his speech became nasal and swallowing difficult. During the last few years, he was unable to stop the urinary stream voluntarily and on occasion had fecal incontinence. Family history was unremarkable.On examination, his speech was