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May 1964

Cerebellar Blood Flow in Man

Author Affiliations

From the Department of Neurology and the Department of Clinical Physiology, Bispebjerg Hospital.
Department of Neurology (Drs. Skinhøj and K. Hoedt-Rasmussen); Department of Clinical Physiology (Dr. Lassen).

Arch Neurol. 1964;10(5):464-467. doi:10.1001/archneur.1964.00460170034005

Recently a method for determination of regional cerebral blood flow in man has been described.1 The method is based on the use of a freely diffusible radioactive indicator. Radioactive krypton 85 (Kr85) dissolved in saline was injected into the carotid artery, and the build-up and subsequent clearance of radioactivity from the brain were followed by a scintillation detector. In a small series of normal subjects the blood flow over the frontal and temporal regions of the hemispheres was about 0.65 ml/gm/min. Low values of about 0.35 ml/gm/min were found over the same regions in patients with dementia due to cerebrovascular disease.

The present report concerns the results of application of the inert gas injection method to the vertebral artery system in order to study the blood flow in the cerebellum.

Material and Methods  Seven hospital patients without clinical evidence of cerebellar diseases were studied. In Table 1 the