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January 1965

Hemangioblastoma and Vascular Malformations As One Lesion

Author Affiliations

From the Neurosurgical Service, Brooke General Hospital, Brooke Army Medical Center, Fort Sam Houston, Texas.

Arch Neurol. 1965;12(1):39-48. doi:10.1001/archneur.1965.00460250043006

The occurrence of a case of an inter-mixture of an arteriovenous malformation and hemangioblastoma of the cerebellum and the realization of its significance in the understanding of these lesions prompted this report. Hemangioblastomas and arteriovenous malformations are relatively common vascular lesions of the brain, but a previous report of their intermixture is unknown to us. Though embryologically these lesions appear to arise from the same structural elements and morphologically there is a resemblance, the arteriovenous malformation exhibits a marked anatomic predilection for the cerebral hemispheres,1-6 while the hemangioblastoma, either single or multiple, as in von Hippel-Lindau's disease, is almost exclusively confined to the cerebellum and other parts of the hindbrain.1,15-19 An arteriovenous malformation is a rare occurrence in the posterior fossa.7-14 An adequate explanation of this difference in location and the inter-relationship of these lesions has not been put forth.

Most authors consider an inter-relationship to

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