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In the preface Dr. H. J. Weitbrecht emphasizes that the author has developed independent thoughts of his own concerning the problem of psychophysical correlations and the structure of psychoorganic diseases; these thoughts, Professor Weitbrecht claims, could be a cornerstone for the concept of a so-called "general psychiatry."
In the introduction Zeh quotes Hoche who in 1912 emphasized the common cause and the common fatal outcome of all cases of general paresis. Later on, particularly in connection with the various forms of treatment, from salvarsan to malaria to penicillin, general paresis became one of the best studied and best known illnesses. But Zeh feels that the correlations between clinical findings on one side and chemical and humoral findings on the other side have been neglected. He sees in general paresis a natural model of somatopsychic correlations which may give information concerning the structure of organic psychoses and interrelations of psychoorganic phenomena.
Alfred Gallinek. Progressive Paralyse (General Paresis).. Arch Neurol. 1965;12(1):111. doi:10.1001/archneur.1965.00460250115018