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March 1965

Hemorrhage Into Pituitary Adenomata: Report of Two Cases With Spontaneous Recovery

Author Affiliations

From the Neurosurgical Services, Boston Veterans Administration Hospital and Massachusetts General Hospital.

Arch Neurol. 1965;12(3):326-331. doi:10.1001/archneur.1965.00460270102013

SINCE Brougham et al6 in 1950 reviewed the literature and reported five new cases of pituitary apoplexy, there has been an increasing interest in the subject. Subsequent physicians22,26,45 reporting their clinical experiences have cited other recorded cases so that the total number now stands at or near 85.2-11,13-15,17-26, 30-33,35-49 We have recently treated two additional patients with spontaneous hemorrhage into pituitary adenomata. The details of these are reported here.

Clinical Summaries  Case 1.—A 63-year-old bricklayer was transferred from another hospital on April 29, 1960, for evaluation of headache, diplopia, drowsiness, nausea, and vomiting of five days duration. In 1954 a routine chest x-ray had shown multiple pulmonary densities which were thought to represent silicosis. However, metastatic tumor was considered, and a lateral skull film taken as part of a routine metastatic bone series showed an enlarged sella turcica. Endocrine studies showed normal 17-ketosteroid and 17-hydroxysteroid excretion values