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April 1967

The Hypothalamus of the Guinea Pig.

Arch Neurol. 1967;16(4):446. doi:10.1001/archneur.1967.00470220110019

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The most valuable part of this short monograph is the illustrations which provide a guide to the anatomy of the guinea pig hypothalamic nuclear masses. The text itself comprises 15 pages only; the rest is taken up by translations into German and Spanish. There are four pages of references, mainly to comparative anatomical data.

The author added another nucleus to the 17 previously known nuclear areas and designated it nucleus magnocellularis praefascicularis mamillaris. This nucleus is indeed a striking aggregation of very large cells medial to the fornix and mamillotegmental tract. The discovery of a hitherto unknown nucleus is evidence enough for the need for this thorough examination of the hypothalamus; and it is surprising that, in spite of the widespread use of guinea pigs in experimental neurology and endocrinology, such a survey has not been available. Although one might expect nowadays an ultrastructural examination of some nuclear areas,

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