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August 1967

"Treatment of Collagen Diseases" and "Treatment of Adrenal Disorders" in Modern Treatment.

Arch Neurol. 1967;17(2):222-223. doi:10.1001/archneur.1967.00470260112016

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This volume is about equally divided between "collagen diseases" and adrenal disorders. The section on adrenal cortisol insufficiency, Cushing's syndrome, adrenal hyperplasia, hyperaldosteronism, and pheochromocytoma are concise and well written summaries. The contributions on the "collagen diseases," with one, possibly two, exceptions, are not critical. The style of writting is heavy. There are statements that confuse. There are, in the reviewer's opinion, statements that cannot be supported by facts. Some examples are (1) "testicular pain" is common in polyarteritis, (2) the "common pathogenesis" of collagen diseases is autoimmunity, (3) systemic lupus erythematosus (SLE) is described as "frequently involving males,"(4) long-term use of chloroquin (250 mg/day) or hydroxychloroquin (400 mg/ day) "may not be associated with a significant incidence of retinal damage," (5) "severe anaphylactic reactions are more common in patients with SLE than others," (6) in systemic sclerosis "frequent remissions and regressions are seen in the untreated patient," (7) "myopathy

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