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The question whether the globus pallidus is of telencephalic or diencephalic origin has found a final solution in this clearly written and convincingly illustrated monograph: It is of diencephalic, more precisely of subthalamic descent. Both of its segments deriving from independent structures are relatives of the subthalamic nucleus.
This conclusion is the result of a meticulous analysis of the brains of 48 human embryos and fetuses, of several human newborns and infants, and of a number of animal (mammalian) embryos and adults. The findings are illustrated in chronological order by beautiful photographs of tissue sections and, for ultimate clarity, by three dimensional reconstruction models designed by the author. Special attention is given to the chronological difference (heterochrony of Kahle) in the depletion of subthalamic and telencephalic matrix and in the maturation of neurons and myelinization of nerve fibers between pallidum and striatum. The discussion is not only concerned with
Lindenberg R. Die Entwicklung des Globus Pallidus und des Corpus Subthalamicum. Arch Neurol. 1968;18(2):219–220. doi:10.1001/archneur.1968.00470320121015
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