This volume of the series contains the papers that were given at the international meeting held in Moscow to celebrate the centennary of Sechenov's classic "Brain Reflexes." The sessions were devoted to three topics and the volume is almost equally divided among them. The first part fittingly was " 'Brain Reflexes' and Central Inhibition" since it was Sechenov and his student Pachutin who discovered inhibition in the central nervous system of frog. Eighteen papers comprise this section. The second part includes 14 papers dealing with various aspects of "General Principles of Self-Regulation in Cortico-Subcortical Correlations." The third is on "Evolutionary Physiology of the Nervous System and Brain Ontogenesis." It includes 13 papers. The large number of papers and the international assemblage of participants provide a cross section of research in the neurophysiology of the higher centers in different countires.