THE TERM "ossifying fibroma" is applied to a localized fibro-osseous dysplasia encountered in the bones of the face and skull which presents clinically and radiographically as a monostotic expansile lesion.1,2 When it occurs at the base of the skull, especially in the orbital roof, an ossifying fibroma appears as a round or oval radiolucency surrounded by a shell of bone. According to Taveras and Wood,3 a meningioma that arises "in relation to air sinuses of the skull, particularly the sphenoid sinus, often produces a characteristic pattern which has been called 'blistering.' " This was first noted by Dyke4 who referred to it as "hypertrophy of the bone forming the posterior ethmoid cells so that these project into the intracranial cavity."
Thus, a blistering meningioma may resemble an ossifying fibroma of the orbital roof or sphenoid5 to some extent radiographically. Histologically, there is also partial similarity.6
Lehrer HZ. Ossifying Fibroma of the Orbital Roof: Its Distinction From "Blistering" or "Intra-osseous" Meningioma. Arch Neurol. 1969;20(5):536–541. doi:10.1001/archneur.1969.00480110100010
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