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August 1969

Hypoglycemic Peripheral Neuropathy

Author Affiliations

Stoke-on-Trent, England
From the North Staffordshire Royal Infirmary, Stoke-on-Trent, England.

Arch Neurol. 1969;21(2):121-132. doi:10.1001/archneur.1969.00480140021002

PERIPHERAL neuropathy is a rare finding in spontaneous hypoglycemia, and only 22 patients have been reported in the literature (Table 1).1-12 The purpose of this communication is to report two additional cases and to analyze the clinical presentation of peripheral neurological symptoms that occasionally accompany spontaneous hypoglycemia.

Report of Cases  CASE 1.—A 49-year-old electroplater was admitted to the hospital on June 24, 1963. He had a history of eight attacks approximately evenly spaced over the preceding 3½ years. The attacks started with sudden jerking movements of the legs, followed by similar movements of the arms, lasting altogether ten minutes. Attacks during the preceding 18 months were more severe, lasted one-half hour, and were accompanied by mental confusion and partial amnesia. The movements were described by the patient's wife as partly writhing and partly jerking; in some attacks, he tore his clothes and fell. She noticed pallor but no

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