RHESUS MONKEY infants in rare instances have exhibited brain damage following spontaneously occurring complications of pregnancy or birth. One infant, following a breech delivery, manifested brain pathological findings typical of asphyxia neonatorum.1 More recently, another infant sustained severe brain damage following an incomplete abruptio placentae. The clinical and pathological findings presented by this case are described in detail because of their richness and complexity and because of their significance to the development of models of perinatal brain damage in the experimental animal.
The expected date of delivery of pregnant monkey I-127 was Nov 22, 1964. When the animal failed to deliver by this date, she was placed under close observation. Repeated abdominal palpation failed to reveal evidence of fetal movements. Fourteen days after the expected date of delivery, the mother was surgically delivered of her infant. It was believed the two week postmature fetus had died
Myers RE. Cystic Brain Alteration After Incomplete Placental Abruption in Monkey. Arch Neurol. 1969;21(2):133–141. doi:10.1001/archneur.1969.00480140033003
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