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March 1970

Renal Failure in Paraplegia.

Arch Neurol. 1970;22(3):285-286. doi:10.1001/archneur.1970.00480210095017

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This small monograph records a careful and detailed histopathological study of 220 autopsies performed on patients with paraplegia at the National Spinal Injuries Centre, Stoke Mandeville, England. Although Dr. Tribe is most concerned with the pathological findings in chronic renal failure, he documents in detail the causes of death and their relationship to the patients' ages, level of paraplegia, and whether the paraplegia was traumatic or nontraumatic in origin. Dr. Silver contributes a concisely written chapter on the diagnostic tests useful in analyzing renal function in such patients and a chapter on amyloidosis, its occurrence, clinical manifestations, pathology, and contribution to the natural history of such patients.

The authors document the contribution of chronic pyelonephritis, hydronephrosis, cystitis, and urinary tract calculosis to the renal hypertension, amyloidosis, and renal failure seen in patients with long-standing paraplegia and tetraplegia. The 50 tables, 63 text figures, and numerous illustrative cases, all from their

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