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April 1971

Concerning Multiple Fibromas of the Skin and Their Relationship to Multiple Neuromas

Author Affiliations

Professor in Strassburg

Arch Neurol. 1971;24(4):375-377. doi:10.1001/archneur.1971.00480340107013

Autopsy: 24 January 1879. Marie Kientz, 55 years old.... Innumerable nodules over almostthe entire epidermis (Plate I), for the most part pedunculated, others sessile, most of them simply spherical, of all possible sizes.... The tumors were most numerous on the skin of the abdomen and he chest, though they were perhaps denser and even larger on the skin of the back.... They sent ramifications into the subcutaneous tissue, ... but were easily palpable through the thinned-out cutis. In addition there were mobiletumors that were entirely subcutaneous....

In general, the skin of the entire body had a dirty brown color, but when examined more closely, there were innumerable pea-sized brown pigmented spots, especially over the thorax and neck, and a larger one (4 × 3 cm.) in the left gluteal region....

On the surface of the small intestine there were two small nodules, both firm.... A Large tumor

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