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April 1971

Angiostrongylosis: In the Pacific and Southeast Asia.

Arch Neurol. 1971;24(4):382. doi:10.1001/archneur.1971.00480340114020

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This monograph summarizes the extensive studies of the authors as well as others on Angiostrongylus cantonensis. Although this nematode parasite of the pulmonary arteries of rats has been known for 35 years it is only in the past decade that its relationship to human eosinophilic meningoencephalitis has been recognized. The life cycle of the parasite has now been established and this has led to world-wide epidemiological surveys. The authors suggest that the parasite originated in Madagascar and spread widely from there. Man probably is infected through the eating of slugs, snails, prawns, planarans, vegetables, and possibly water. Although there are relatively few thoroughly documented cases of human infection, the clinical picture is well described. Fortunately, the great majority of the infections are not severe and are self limited. At present, chemotherapy leaves much to be desired. The bibliography of angiostrongylosis is extensive in spite of the short history and fortunately

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