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Article
June 1971

The Sign of "Tingling" in Lesions of the Peripheral Nerves

Arch Neurol. 1971;24(6):574-575. doi:10.1001/archneur.1971.00480360108016
Abstract

Too often there is difficulty making a precise diagnosis in peripheral nerve lesions. Is the nerve divided, compressed, lacerated, or irritated? Is regeneration occurring? Is the palpable neuroma permeable to the axons? Has a sutured nerve reunited? ....

We think that the systematic study of tingling provoked by pressure on a nerve can help to answer these questions.

Pressure on a damaged nerve trunk often produces a tingling sensation, projected to the periphery of the nerve and localized to a very exact cutaneous area.

It is important to differentiate this tingling from the pain sometimes produced by pressure on an injured nerve. The pain is a sign of irritation of the nerve; tingling is a sign of regeneration; or more precisely, tingling indicates the presence of young axons, in the process of growing.

The pain of nerve irritation is almost always local, perceived at the point where the

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