Too often there is difficulty making a precise diagnosis in peripheral nerve lesions. Is the nerve divided, compressed, lacerated, or irritated? Is regeneration occurring? Is the palpable neuroma permeable to the axons? Has a sutured nerve reunited? ....
We think that the systematic study of tingling provoked by pressure on a nerve can help to answer these questions.
Pressure on a damaged nerve trunk often produces a tingling sensation, projected to the periphery of the nerve and localized to a very exact cutaneous area.
It is important to differentiate this tingling from the pain sometimes produced by pressure on an injured nerve. The pain is a sign of irritation of the nerve; tingling is a sign of regeneration; or more precisely, tingling indicates the presence of young axons, in the process of growing.
The pain of nerve irritation is almost always local, perceived at the point where the
Tinel J. The Sign of "Tingling" in Lesions of the Peripheral Nerves. Arch Neurol. 1971;24(6):574–575. doi:10.1001/archneur.1971.00480360108016
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