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September 1971

Neurotransmitter und Neuromodulatoren.

Arch Neurol. 1971;25(3):285-286. doi:10.1001/archneur.1971.00490030111026

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Hordes of neurophysiologists crawled all over the cortex, and the effects of stimulation or ablation on electrical activity and function became their daily occupation. More refined methods, particularly microelectrophoresis and recordings from single cells anywhere in the nervous system, have not yet dampened their enthusiasm and have made their work more meaningful and results somewhat neater and easier to interpret. Pharmacologists have joined the crowd and, to their delight, the responses of single cells to microvolumes of drugs can now be measured.

Numerous reviews of the often contradictory results of peripheral and central microelectrophoresis have been published, but this monograph is particularly useful to those who contemplate using the technique for the first time. It describes the methods used in detail and also the effect of neurotransmitter and neuromodulator substances, as well as "candidate transmitter." Perhaps the most useful section of this book is a formidable table which summarizes the

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