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World interest in and organized studies on the problems of multiple sclerosis (MS) have increased and expanded remarkably in recent years but, as yet, these endeavors have not brought precise answers to the question of etiology. But, as investigations on many fronts proceed, evidence is accumulating to show that in the assessment of cause and pathogenesis, many different factors must be considered. In a broad conceptual sense, it is now recognized that MS must be viewed as being the result of external, environmental factors (? a specific agent) acting upon individuals of varying susceptability and that there are differing degrees of tissue reaction which influence the fluctuating changes in central nervous system function to explain the complex clinical entity. J.H.D. Millar, neurologist to the Royal Victoria Hospital, Belfast, Ireland, has actively participated in the study of MS in northern Ireland for more than 20 years. In this succinct, remarkably compact monograph,
Rose AS. Multiple Sclerosis: A Disease Acquired in Childhood. Arch Neurol. 1971;25(4):383. doi:10.1001/archneur.1971.00490040109018
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