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June 1972

Tropomyosin and Troponin in Normal and Dystrophic Human Muscle

Author Affiliations

From the departments of neurology and pediatrics, University of Pittsburgh School of Medicine, and Children's Hospital of Pittsburgh, Pittsburgh.

Arch Neurol. 1972;26(6):547-550. doi:10.1001/archneur.1972.00490120087010

The two subunits of tropomyosin in cat fast and slow and human vastus lateralis muscles were electrophoretically identical, while the slower migrating cardiac tropomyosin unit was different. One troponin protein, band 5a, was electrophoretically different when cat fast and slow and cat heart and slow muscles were compared. There were no qualitative differences in the electrophoretic patterns of tropomyosin and troponin from normal and Duchenne dystrophic human skeletal muscle.

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