[Skip to Navigation]
October 1972

Protein and Enzyme Alterations in Experimental Brain Injury

Author Affiliations

From the Division of Neurological Surgery and the Department of Biochemistry, Pritzker School of Medicine, University of Chicago.

Arch Neurol. 1972;27(4):314-321. doi:10.1001/archneur.1972.00490160042006

Increased intracranial pressure was produced in the cat by epidural balloon compression. An increase in the activity of sodium-potassium-adenosine triphosphatase was detected in compressed brain compared to the control brain. Alterations in the acetylcholinesterase isozymes were detected with polyacrylamide electrophoresis. Evidence obtained by immunological means suggests the release of synaptic membrane antigens following cerebral injury.

Add or change institution