[Skip to Navigation]
August 1973

Lack of Levodopa Effect on Preexisting Temporal Lobe Focus

Author Affiliations

Ann Arbor, Mich
From the departments of neurology (Drs. Newman and Kooi) and psychiatry (Drs. Tucker and Kooi), University of Michigan Medical Center, Ann Arbor.

Arch Neurol. 1973;29(2):122-123. doi:10.1001/archneur.1973.00490260066014

Three patients with parkinsonism treated with levodopa had abnormal pre-levodopa and stabilization levodopa electroencephalograms with focal sharp and spikewave activity. There were no seizures and no significant EEG changes with levodopa treatment. This suggests that levodopa may not aggravate a preexisting seizure tendency, as suggested by the EEG.

Add or change institution