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January 1974

Behavioral Studies

Arch Neurol. 1974;30(1):23-26. doi:10.1001/archneur.1974.00490310025004

Behavioral studies have been reviewed extensively in other sections of this report. This summary will review and evaluate those studies that firmly relate aggressive behavior with brain function and will present a concise statement about this relationship. Because there are unresolved issues in the definition of aggression and because of species differences, it is important that investigations be identified where behavior is directly measured as a function of stimulation or ablation of specific brain areas. With due respect for species differences, some general principles can be formulated about the relation of aggression to brain function in both man and animals.

The midbrain has a number of areas within it that are related to rage or defensive threats and to varieties of attack. Electrical stimulation of the central gray of the midbrain can elicit a defensive display in the cat in which the cat's hair is raised, its ears are