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Article
March 1974

Hereditary Brachial Neuropathy: Report of Two Families

Arch Neurol. 1974;30(3):252-254. doi:10.1001/archneur.1974.00490330060010
Abstract

Based on findings from two patients with hereditary brachial neuropathy and their families, an autosomal dominant mode of inheritance with high penetrance is suggested. The first attack usually occurs before age 20. Most patients have several attacks, infrequently more than four. The likelihood of further episodes of neuropathy decreases with age. Longrange prognosis is good except for occasional minor neurological deficits usually involving proximal muscles of the upper extremities. Based on electromyographic and nerve conduction studies, patients with this disorder do not appear to have a generalized neuropathy. The clinical picture of hereditary brachial neuropathy is indistinguishable from nonfamilial brachial plexus neuropathy except for earlier onset, recurrence of attacks, and family history.

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