Electrodiagnostic studies were performed at the time of peak neurological deficit in 26 episodes of the Guillain-Barré syndrome, and at intervals before and after this time in 13 cases. Of the patients 65.4% had made a complete clinical recovery at the termination of the study. The shortest recovery time from the onset of symptoms was four weeks and the longest was 34 weeks. A rapid recovery was associated with an acute progression of neurological deficit in the face of normal electrophysiologic study results throughout the illness (19.2%). Patients requiring the longest time to recover demonstrated various electromyographic abnormalities, but, in particular, all showed evidence of denervation (fibrillation, positive sharp waves, or both).
Eisen A, Humphreys P. The Guillain-Barré Syndrome: A Clinical and Electrodiagnostic Study of 25 Cases. Arch Neurol. 1974;30(6):438–443. doi:10.1001/archneur.1974.00490360014004
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