Denervation of the rat hind limb was found to increase the K+-independent p-nitrophenylphosphatase (basic pNPPase) activity of the isolated sarcolemma. There was no change in K+-stimulated p-NPPase and Na+, K+-stimulated adenosine triphosphatase. This increased enzyme activity might underlie the postspike increase in K+ conductance of denervated sarcolemma in view of the proposal that basic p-NPPase activity is related to the rate of passive flux of K+.
Brody IA. p-Nitrophenylphosphatase in Denervated Muscle. Arch Neurol. 1974;31(5):317–319. doi:10.1001/archneur.1974.00490410065006
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