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February 1975

Dyskinesia—An Unusual Reaction to Ethosuximide

Author Affiliations

From St. Joseph's Hospital and the Department of Medicine, McMaster University Medical School, Hamilton, Ontario, Canada.

Arch Neurol. 1975;32(2):137-138. doi:10.1001/archneur.1975.00490440087017

A 15-year-old girl was given two 250-mg doses of ethosuximide because of petit mal seizures. Within hours of taking the first pill she developed an acute reaction involving dyskinetic movements of the face, arms, and legs. These were abruptly and completely relieved by an intravenous injection of diphenhydramine hydrochloride.

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