• Three days after an episode of hypoxia, a 20-year-old man developed profound motor deficit in the absence of behavioral or cognitive disturbance. Previous reviews of delayed hypoxic encephalopathy have stressed behavioral and cognitive disturbances as the initial symptoms. This patient's pyramidal tract dysfunction in the absence of higher cortical dysfunction serves to illustrate that delayed hypoxic encephalopathy is predominantly a white matter rather than a gray matter disorder.
Devereaux MW, Partnow MJ. Delayed Hypoxic Encephalopathy Without Cognitive Dysfunction. Arch Neurol. 1975;32(10):704–705. doi:10.1001/archneur.1975.00490520074013
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