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October 1975

Delayed Hypoxic Encephalopathy Without Cognitive Dysfunction

Author Affiliations

From the Section of Neurology, Department of Medicine, Navy Regional Medical Center, Philadelphia, the Division of Neurology, Hahnemann Medical College, Philadelphia, and the departments of neurology of Rancocas Valley Hospital, Willingboro, NJ, and the University of Pennsylvania.

Arch Neurol. 1975;32(10):704-705. doi:10.1001/archneur.1975.00490520074013

• Three days after an episode of hypoxia, a 20-year-old man developed profound motor deficit in the absence of behavioral or cognitive disturbance. Previous reviews of delayed hypoxic encephalopathy have stressed behavioral and cognitive disturbances as the initial symptoms. This patient's pyramidal tract dysfunction in the absence of higher cortical dysfunction serves to illustrate that delayed hypoxic encephalopathy is predominantly a white matter rather than a gray matter disorder.

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