[Skip to Content]
[Skip to Content Landing]
March 1976

Scanning Electron Microscopy Studies in Muscular Dystrophy

Author Affiliations

From the Department of Microbiology and Immunology (Dr Miller) and the Division of Neurology, Department of Medicine (Drs Roses and Appel), Duke University Medical Center, Durham, NC.

Arch Neurol. 1976;33(3):172-174. doi:10.1001/archneur.1976.00500030028005

• Scanning electron microscopy of unmanipulated erythrocytes from patients with myotonic dystrophy or Duchenne dystrophy and patients who were Duchenne carriers showed a large increase in the number of stomatocytes over the number in normal controls. No specific morphologic changes that would differentiate any of the dystrophic patients from one another were seen. Adverse conditions such as washing before fixation or extreme pH produced a greater change in erythrocytes from these patients than in those from normal controls.