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March 1976

Midbrain Corectopia

Author Affiliations

From the Neuro-Ophthalmology Unit, departments of neurological surgery, neurology, and ophthalmology, University of California, San Francisco.

Arch Neurol. 1976;33(3):193-195. doi:10.1001/archneur.1976.00500030049010

• Intermittent corectopia was recently observed in a patient with bilateral, rostral midbrain infarction. Results from neuropathologic examination disclosed isolated but intact Edinger-Westphal nuclei.

An explanation of midbrain corectopia centered on segmental innervation of the pupil by the Edinger-Westphal nucleus. In the presence of a paralyzed dilator muscle, select, central inhibition of sphincter tone resulted in an oval and eccentric pupil.