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August 1976

Fungal Aneurysms of Intracranial Vessels

Author Affiliations

From the Department of Pathology, New York Hospital-Cornell Medical Center, New York. Dr Horten is now with the Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York. Dr Abbott is now with the Department of Neuroradiology, New York Hospital.

Arch Neurol. 1976;33(8):577-579. doi:10.1001/archneur.1976.00500080055008

• Intracranial fungal aneurysms arise from major cerebral arteries. Fungi directly invade vessel walls from the luminal surface (fungal emboli) or from the adventitia (fungal meningitis). The vasa vasorum are free of fungi. Aneurysmal rupture is common with extensive hemorrhagic necrosis of the surrounding brain. Aspergillus is the usual causative agent; its sources are nasal sinusitis or endocarditis.

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