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August 1976

Science and Epilepsy: Neuroscience Gains in Epilepsy Research

Arch Neurol. 1976;33(8):591. doi:10.1001/archneur.1976.00500080069017

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This book is James O'Leary's last work, and reflects the many-faceted accomplishment of fine clinical and scientific neurologists. Traditionally, epilepsy always has lain close to the heart of the electrophysiologist and cerebral localizer, for seizure patterns not only reflect the functional neuroanatomy of the brain, but imply something of the mixed stimulation-inhibition of neurological function. O'Leary and Goldring use the story of epilepsy to take us through progressive understandings of the brain and its paroxysmal disease from earliest times to the present, devoting chapters to the development of the neurone doctrine, electrophysiology, localization, the electroencephalogram, and the brain stem reticular core. It also reviews some of the more specific physiologic, anatomic, and pharmacologic abnormalities of the epilepsies. The chemistry of the epilepsies receives short shrift, but that was neither O'Leary's nor Goldring's main interest, and a book as good as this can hardly be criticized because it isn't something else.

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